Born in Philadelphia, Pennsylvania in 1955, Vincent Desiderio is an American realist artist. He studied fine art and art history at Haverford College in Pennsylvania where he graduated in 1977. He spent the following year studying in Florence, Italy at the Accademia di Belle Arti and 1979 through 1983 studying at the Pennsylvania Academy of the Fine Arts.

His figurative works are uncanny and mysterious. The compositions frequently include human figures within strange and often unfamiliar spaces. Desiderio employs meticulous detail to create his large-scale canvases and triptychs inspired by his own life experiences, modern day, and Western art history.  

Desiderio has received numerous awards and grants including a Pollock-Krasner Foundation Grant, two National Endowment for the Arts Grants, Everson Museum of Art Purchase Prize, a Creative Artists Network Rome Grant, a Cresson Traveling Scholarship from the Pennsylvania Academy of the Fine Arts, and the International Contemporary Art Prize awarded by the Prince Ranier Foundation of the Principality of Monaco. His work is included in the collections of the Pennsylvania Academy of Fine Arts in Philadelphia, Pennsylvania; Metropolitan Museum of Art in New York, New York; Hirshhorn Museum and Sculpture Garden in Washington, D.C.; Denver Art Museum in Denver, Colorado; and Everson Museum of Art in Syracuse, New York. Desiderio currently works and resides in Sleepy Hollow, New York.